Life Imaging Center (LIC) Zentrum für Biosystemanalyse IMAGING-Home

Life Imaging Center
Center for Biological Systems Analysis (ZBSA)
Habsburgerstr. 49
D-79104 Freiburg

Phone +49/761/203-2934
Fax +49/761/203-2941

Use for your first contact with the LIC the above mail address and fill out the LIC application sheet, which you find here.

How to reach and find us:

on the MAP Building #7; ground floor - office rooms: 00.033 and 00.034

News 1:

Core Facility Management Software Workshop

on the 7th and 8th of February 2017 in Freiburg, Germany.

Due to the increasing number of core facilities (to name Imaging, Proteomics,Metabolomics, Genomics…) there is a high demand for efficient quality management and especially booking solutions. Major topics of the workshop will include: case reports from the field (core facility managers), presentations of commercially available solutions (industry) as well as hands‐on experience to understand the main concepts of the available solutions. Additional round-up discussions should elucidate the actual requirements.

It is primarily designed to meet the requirements of core facility managers, looking for the optimal solution, as well as team or IT members, who will have to setup such a management software in their home institutions. We also encourage major opinion leaders in the field to use this workshop as an opportunity to discuss and define the future needs in the field.

The registration fee of 50 € covers finger food and refreshments during the workshop.

Download further information and program

Online registration, here

Deadline for registration: January, 20th 2017.


News 2:

1st MIAP BioImage Analysis Workshop

A basic Introduction for Life Scientists into ImageJ/Fiji and KNIME Image Processing

31st January – 2nd February 2017
Center for Biological Systems Analysis (ZBSA)
Freiburg University

Microscopy and Image Analysis Platform (MIAP), Freiburg Bioimaging Center (BIC), Konstanz

The 1st MIAP Bioimage Analysis Workshop intends to provide life scientists without advanced knowledge in image analysis an introduction into basic and state-of-the-art concepts of digital image processing using ImageJ/Fiji and the integrative software platform KNIME. The course will cover object segmentation, counting, feature extraction and colocalization. The aim is to provide the participants a portfolio of knowledge and solutions for basic bioimage analysis tasks.

- ImageJ/Fiji

( / / represent the most widespread image analysis tools which are supported by a world-wide developer and user community. The open-source software is designed for scientific multi-dimensional images and is highly extensible, with thousands of plugins and scripts for performing a wide variety of tasks.


( represents a large integrative open-source data mining platform featuring a user friendly graphical interface which enables basic users to design workflows for data analysis in a highly efficient manner.


The KNIME Image Processing extension KNIP ( provides integrations of ImageJ/ImageJ2 and others, thus comprising functionalities as offered by the integrated tools in addition to the functionality inherited from KNIME itself.

The registration fee of 75€ covers finger food and refreshments during the workshop.

Download further information and program

Online registration, here

Deadline for registration: January, 15th 2017.


We hope to see you soon in Freiburg!

Your MIAP Coordination Team



LIC News: General

The LIC was successful in the  DFG Call for "Core Facilities and Networks 2015" Freiburg has been awarded a grant over three years  for realization of the Microscopy and Image Analysis Platform Freiburg (MIAP-Freiburg).

MIAP-Freiburg will establish a series of interdisciplinary seminars and workshops covering in great depth special topics in microscopy and related fields. The activities, which are arranged as a cooperation of academia and industry, are targeted towards scientific users of microscopical techniques in the life and material sciences, computer scientists in the area of image analysis and software development, engineers and physicists from basic research, instrument developers in the whole area of microscopy and finally staff from imaging facilities world-wide.


Moreover the LIC application as an "Advanced Light Microscopy Multi Modal Single Sited Node" within EuroBioImaging was excellently reviewed by an independent International Evaluation Board and received the final ranking: Highly Recommended Expression of Interest for Euro-BioImaging Node. All the details of the review you find here.

The LIC is listed in the database Research Infrastructure Portal: RIsources of the German Research Foundation (DFG). For more details see here.


Overview of scientific publications from research groups done by using LIC infrastructure and support

LSM-U-2	ZEISS LSM 510 META with upright microscope Axio Imager Z1

Within the last five years (2010 – Oct 2015) the workgroups using the LIC infrastructure have published more than 256 publications (only 85% of the workgroups responded to our requests) containing images or data recorded in the LIC with a pooled number of 1943.9 Impact Factor points (mean 7.9 IF/per publication). This included 73 publications with an IF higher than 9, 51 publications IF >10 and 19 publications IF >15.

The majority of publications where in the field of Cell Biology (n=118, mean IF 8.5 ), followed by Developmental Biology (n=47, mean IF 8.1), Neurobiology (n=46, mean IF 7.3 ) and Plant Biology (n=21, mean IF 6.6). Structural Biology, connected with biological imaging is new covered in Freiburg since 2012 and therefore we reached here only n=3 but with a mean IF of 13.7


LIC General Information:

The Life Imaging Center (LIC) is a central core facility of the Albert-Ludwigs-University Freiburg open to members of all Faculties. Currently 250 active users from 6 Faculties (Biology; Medicine; Chemistry and Pharmacy; Mathematics and Physics; Environment and Natural Resources; and Engineering) are using the infrastructure of the LIC. The users come from app. 84 workgroups and the usage time of the microscopes in 2011 was about 23.000 hours. We have now approximately 60 - 80 new users per year and the same number leaving the facility. Outside users from Freiburg (Max Planck Institutes, Fraunhofer Gesellschaft) and from other universities are also welcome. For the details of application follow this link.

The LIC has now 14 rooms in the ZBSA with app. 400 m² (9 microscope rooms with 19 microscope set-ups, wet lab, large cell culture room, and large computer lab for 11 high-end workstations + 8 smaller desktop computers) plus 2 rooms with 3 LSMs (35 m²) in a neighboring building.


Take a Tour through the Life Imaging Center (LIC) (only for Windows Explorer)

 Start the tour

The Life Imaging Center, which is now one of the largest facilities of that type in Germany, was founded in 2000 by W. Driever and R. Nitschke as the central project Z2 of the SFB 592 "Signaling mechanisms in embryogenesis and organogenesis". The LIC was originally located in the Institute of Biology I and moved in April 2008 into the new building of the Zentrum für Biosystemanalyse (ZBSA) in Habsburgerstr. 49. With the move into the ZBSA, the LIC also merged with the Imaging Core Facility of the Medical Faculty founded in 2003 by R. Nitschke and M. Frotscher. The LIC works tightly together and shares equipment and software licenses with the Imaging facility of Max Planck Institute for Immunbiology and Epigenetics (MPI-IE) in Freiburg.





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